NANOPARTICLE-BASED THERAPEUTICS TO OVERCOME OBSTACLES IN THE TUMOR MICROENVIRONMENT OF HEPATOCELLULAR CARCINOMA

Nanoparticle-Based Therapeutics to Overcome Obstacles in the Tumor Microenvironment of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is still a main health concern around the world, with a rising incidence and high mortality rate.The tumor-promoting components of the tumor microenvironment (TME) play a vital role in the VITAMIN C CALCIUM ASCORBATE 1000MG development and metastasis of HCC.TME-targeted therapies have recently drawn increasing interes

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Riga-Fede disease: report of a case in an infant

Riga-Fede disease (RFD) is a rare, benign condition found in infants, characterized by ulcers in the oral mucosa, around the tongue and gums.It is caused by VITAMIN C CALCIUM ASCORBATE 1000MG repeated injuries, caused by movements of the tongue over the lower incisors.It usually coexists with neonatal teeth.Although it starts as a small ulcer, it c

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Study on the mechanical characteristics of sand pebble surrounding rock considering the disturbance effect of tunnel excavation

When conducting tunnel construction in sandy gravel strata, disturbance to the sandy gravel soil is inevitable, resulting in alterations to the properties of the surrounding rock.This paper investigates Necklaces the relationship between the relative density (Dr) and shear strength parameters under different disturbance states through the implement

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